Signs of improvement in stage II of membranous nephropathy include reduction or disappearance of foam in urine, return of urine volume to normal, disappearance of edema, etc. Membranous nephropathy mainly leads to a large amount of urinary protein, and the signs of improvement of patients are the reduction of urinary protein, mainly manifested by the reduction and disappearance of urine foam, the recovery of urine volume, the reduction or disappearance of edema, and so on. However, the above indexes are subjective and cannot reflect whether membranous nephropathy is getting better or not. At this time, we need to go to the hospital to improve the urine routine, 24-hour urine protein quantification, renal function and other related examinations. Anti-phospholipase A2 receptor antibody is closely related to the severity of membranous nephropathy, and the improvement of membranous nephropathy can also be reflected by monitoring this index. Even if membranous nephropathy improves, the medication should not be stopped immediately, and you need to continue to take the medication according to the doctor’s instructions, otherwise the disease may recur. It is recommended that patients with membranous nephropathy should consult regular hospitals in time and take standardized treatment under the guidance of physicians.