Ursodeoxycholic acid, omeprazole and atropine are recommended for post gallbladder surgery syndrome. Post-operative gallbladder syndrome refers to the disappearance of the original symptoms after surgery, but the emergence of digestive symptoms and biliary symptoms, mainly manifested as epigastric distension, dyspepsia, loss of appetite, biliary colic, abdominal pain, jaundice and other symptoms. Patients with the above symptoms can take ursodeoxycholic acid tablets and omeprazole under the guidance of the doctor to treat bile reflux gastritis and relieve digestive discomforts; atropine is an anticholinergic drug that can relieve biliary colic, abdominal pain and other discomforts. Post-operative gallbladder syndrome medication should be taken under the guidance of a doctor, not blindly use medication, daily attention should be paid to regular review, monitoring the changes in symptoms, and timely consultation when discomfort occurs. Pay attention to the light diet, eat small meals, avoid greasy spicy food.