Acne vulgaris is epidermoid cyst, manifested as hemispherical elevation of the skin, hard, elastic, and painful when secondary infection occurs, usually applied with antibiotic ointment when secondary infection occurs, such as erythromycin ointment, metronidazole gel, and mupirocin ointment. 1. Erythromycin ointment: this product is a macrolide antibiotic, most gram-positive bacteria, part of the gram-negative bacteria have antibacterial activity, suitable for sebaceous cysts due to Aureobasidium and other infections caused by the inflammation of the treatment. 2. Metronidazole Gel: It is suitable for the treatment of sebaceous cyst inflammation caused by anaerobic bacterial infections. Its nitro group can be reduced to a kind of cytotoxicity, so as to play a role in the metabolism process of bacteria, and promote the death of cells. 3. Mupirocin ointment: It is suitable for the treatment of sebaceous cysts caused by gram-positive cocci, which can hinder the synthesis of bacterial amino acids, and at the same time depletes the intracellular tRNA, so that the RNA and protein synthesis of the sensitive bacteria is aborted, thus playing an antibacterial role. There are many other creams that can be used to treat inflamed sebaceous cysts, and all medications should be used as prescribed by your doctor. If topical ointments are not effective, then surgical removal is required. It is recommended to go to a regular hospital, consult with a professional doctor, and cooperate with the doctor to complete the relevant examinations to clarify the cause, and avoid self-treatment.