There are two common causes of pressure pain in the location of the appendix, one is appendicitis and the other is intestinal diseases such as appendicitis and colitis. Abdominal pain is a typical early symptom of appendicitis, which is a reflex pain from the visceral nerves, and when the doctor presses on it, the patient will experience localized pressure pain. When there is an acute attack, there will also be pain in the upper abdomen or around the navel at the beginning, with the option of surgical removal of the appendix. The pain of gastroenteritis may also be accompanied by gastrointestinal discomfort, such as nausea, vomiting, and diarrhea, which can be treated with oral anti-inflammatory drugs. If there is mild pressure pain in the appendix area, you can choose to observe it first. If the pain is more severe, you need to go to the hospital for relevant tests to clarify the diagnosis.