There are many reasons why female patients experience pain in the thigh bone, such as endocrine disorders during menstruation or endocrine disorders, which can lead to calcium loss in the thigh bone, osteoporosis in the thigh, and painful muscle metabolism disorders. In female patients, fatigue damage to the thigh muscles can occur due to cold or chronic strain, and the accumulation of lactic acid can cause pain and swelling. Female patients with thigh pain need to reduce the weight of the lower limbs, pay attention to warmth, and can take the right symptomatic treatment to reduce the pain level.