What happened to high glutamate dehydrogenase?

The normal value of glutamate dehydrogenase is 2-12 units per liter. The level of glutamate dehydrogenase directly reflects the level of liver cell damage and is a very sensitive indicator of liver function. High levels of glutamate dehydrogenase indicate serious liver damage, because glutamate dehydrogenase is the most abundant enzyme in the human liver, so the main reason for high glutamate dehydrogenase levels is liver cell damage. It is most sensitive in reflecting alcoholic liver cell damage, because alcohol-induced liver cell damage is mainly mitochondrial damage in liver lobular cells, and most of glutamate dehydrogenase exists in mitochondria in liver lobular cells, so liver damage including acute hepatitis, viral hepatitis, toxic hepatitis, liver fibrosis, and cirrhosis are the ultimate causes of elevated perine dehydrogenase. In addition, when glutamate dehydrogenase is too high, it increases the chance of high mutation of glutamate dehydrogenase, and mutation of glutamate dehydrogenase tends to cause congenital hyperinsulinemia, which is an inherited disorder that can together cause hypoglycemia in infants or children.