Blood in sputum can be seen in tuberculosis, bronchodilatation, pulmonary edema, lung cancer, pulmonary infarction, pneumonia and other diseases, and whether it can be self-healing often depends on the cause of the disease, and the prognosis is different for different causes. 1. Tuberculosis: it will not be cured by itself, the treatment is mainly chemotherapy, the treatment program is divided into intensive and consolidation period, the commonly used anti-tuberculosis drugs are isoniazid, rifampicin, pyrazinamide, ethambutol and so on. 2. Bronchodilatation: it will not be cured by itself, oral carbachol can be used to treat hemoptysis, the treatment is mainly to control the infection, ampicillin, imipenem, amoxicillin and other anti-infective drugs, if there is ventilation dysfunction can be used to use bronchodilators, such as budesonide formoterol, salbutamol and so on, to improve the airflow limitation. 3. Pulmonary edema: it will not be cured by itself, drug treatment mainly uses diuretics such as furosemide, vasodilator drugs can choose nitroglycerin, and digoxin can be chosen to enhance myocardial contractility. 4. Lung cancer: it will not be cured by itself and needs active treatment. Early stage can choose surgical treatment, according to the pathological type, gene mutation and other discretionary application of targeted drugs such as gefitinib, crizotinib and so on. 5. Lung infarction: the infarction site will not be self-healing, treatment can choose heparin, streptokinase and other anticoagulant thrombolytic drugs, or surgery to remove the thrombus. 6. Pneumonia or bronchitis: minor respiratory tract infections caused by coughing and rupture of small blood vessels may be able to heal themselves, while severe cases should choose appropriate antibiotics such as penicillin and moxifloxacin, or else they will not be able to heal themselves. When there is blood in the sputum may also have other reasons, should actively seek medical attention, clear cause, under the guidance of a professional doctor targeted treatment, not blindly waiting for self-cure to prevent delays.