The generic name of Tonic Jiale is estradiol valerate tablets, and taking estradiol valerate tablets for breast enlargement may aggravate the condition. Under the action of endocrine hormones, especially estrogen, the mammary glands may have hyperplasia and regrowth with the change of menstrual cycle. Due to certain factors, it may lead to the imbalance of the metabolism of endocrine hormones in the organism, which may cause the level of estrogen to increase, resulting in the over-hyperplasia of mammary tissues as well as the incomplete regrowth of breast tissue, and if the proliferated mammary tissues cannot be completely subsided, then it will lead to the mammary gland hyperplasia. Estradiol valerate tablets are estrogenic drugs, so patients with breast hyperplasia may cause aggravation of the symptoms of breast hyperplasia after taking them. Patients should use medicines that detoxify the liver, activate blood circulation and disperse knots under the guidance of a doctor in order to regulate breast hyperplasia, and at the same time should undergo regular review so as to observe the changes of breast hyperplasia. Patients with jianyi breast hyperplasia should follow the doctor’s instructions for treatment and review, and should not take medication privately.