Leukoaraiosis is not completely self-healing. In other words, there is no effective cure for the disease, but the progression of the disease can be controlled by treating the corresponding symptoms. However, even with active treatment, leukoaraiosis cannot be completely cured, or it cannot be cured without treatment. It is only the symptoms that need to be treated in each patient. In the acute stage of leukoaraiosis, patients should be given general supportive and symptomatic therapy, bed rest, control of mouth and pharyngeal infections, and attention to rest. In addition, after the occurrence of corresponding oral ulcers as well as genital ulcers, it is necessary to go to the dermatology and stomatology department to prescribe some topical drugs for external use. Depending on the symptoms of eye diseases, ophthalmology should be consulted for symptomatic treatment and application of topical drugs. After leukoaraiosis, the general systemic treatment needs to be monitored by a general practitioner or a particularly experienced doctor, and the common medications are glucocorticoids, thalidomide, colchicine, the new drug lenalidomide, biologics, and immunosuppressive agents.”