Hepatitis B DNA is primarily used to assess the level of viral replication in hepatitis B-infected patients, and a high viral load is suggested simply by a hepatitis B DNA of 1.109 x 10^4, but it is not possible to assess the severity of the disease. To assess the severity of hepatitis B, the following aspects should be evaluated comprehensively: 1. ALT (alanine aminotransferase), AST (alanine aminotransferase): it can reflect the degree of hepatocellular damage to a certain extent. 2. Imaging judgment: such as ultrasound, CT, magnetic resonance, can timely understand the presence of cirrhosis and signs of portal hypertension, to find the occupying lesions and the nature of chronic hepatitis B disease progression monitoring. 3. Pathological diagnosis: it can assess the degree of liver inflammation, necrosis and fibrosis, and the presence or absence of fibrosis. Hepatitis B is a chronic disease, if not standardized treatment can develop into cirrhosis, liver failure, liver cancer and other serious diseases. Hepatitis B needs to be diagnosed in specialized hospitals and treated regularly. In daily life, it is necessary to pay attention to the prohibition of drinking and smoking, and pay attention to the strengthening of rest, regular work and rest and relaxation of the mind.