Trimethoprim and budesonide nasal spray belong to the glucocorticoid nasal spray, the difference mainly lies in the drug specifications, indications and contraindications, adverse reactions, etc., the specific use of medication must follow the doctor’s instructions. 1. Drug specifications: the common specifications of Trenbolone Nasal Spray are 120, 180, 240 or 300 sprays per bottle, each containing Trenbolone 55 micrograms; Budesonide Nasal Spray is more often seen in the bottle of 120 sprays per spray containing Budesonide 32 micrograms or 64 micrograms specifications. 2. Indications: Tretinoin Nasal Spray is suitable for the treatment of perennial or seasonal allergic rhinitis; Budesonide Nasal Spray, in addition to allergic rhinitis, is also suitable for the treatment of perennial non-allergic rhinitis, and for the symptomatic treatment after the removal of nasal polyps to prevent their regeneration. 3. Contraindications: Tretinoin Nasal Spray is contraindicated in people who are allergic to this drug; Budesonide Nasal Spray is also contraindicated in people who are allergic to any of its components. 4. Adverse reactions: Tretinoin Nasal Spray may cause cough, epistaxis (nosebleed), headache and other adverse reactions; budesonide nasal spray adverse reactions are common local nasal irritation, nasal cavity mild hemorrhagic secretion and so on. In summary, people who have the need to use trimethoprim or budesonide nasal spray must choose and standardize the use of the drug under the guidance of a doctor, and should not blindly use the drug or increase or decrease the dosage on their own, so as to avoid inappropriate interventions, resulting in adverse consequences.