Cranial defects are harmful and need to be repaired in time: There are many accidents in life every day, and cranial defects are a common one. When a small piece or half of a complete skull is lost, it makes the patient’s skull look asymmetrical on both sides and has a significant impact on the patient’s neurological recovery. PEEK is the new trend when it comes to skull repair. Like traditional animal bone materials, metal materials, hydroxyapatite and calcium phosphate bone cement, most have been gradually eliminated because of varying degrees of rejection, complications or poor insulation. In recent years, polyetheretherketone peek polymer material has gradually become a new material for cranial bone repair because of its good biocompatibility, ability to complex plasticity, excellent mechanical properties, good protective properties and high postoperative comfort. So, cranial repair peek rejection, postoperative sequelae? 4 technical innovation, upgrade PEEK cranial repair plastic surgery: polyether ether ketone peek material for cranial repair, and then according to the CT data for personalized three-dimensional design, postoperative rejection infection rate is low, there is basically no sequelae, good results, loved by patients. In recent years, we have summarized and researched and improved hundreds of completed peek skull repair surgeries, realized four technical innovations, and successfully upgraded the technology to the new PEEK skull repair plastic surgery. This technique introduces the concept of plastic surgery, and makes a personalized and thorough skull repair and cosmetic plan for each patient with skull defect; and further enhances and improves the details of the surgery, so that the overall skull is natural and beautiful after surgery.