The best way to get rid of acne is to target the pathogenesis of acne, that is, acne for comprehensive conditioning. The pathogenesis of acne is mainly due to increased sebum secretion from the follicular sebaceous glands, while the follicular pore openings are blocked, so that sebum accumulation is followed by bacterial infection and inflammatory reaction, so that acne is formed. In terms of treatment, the following links should be targeted for intervention: 1. First, we should reduce sebum secretion, including a light diet, do not eat too much spicy, greasy and stimulating food, and eat less sweets. In addition, sebum secretion is often related to endocrine and hormone, especially androgen level, so if there is an endocrine disorder, it should also be treated, so as to really reduce sebum secretion. 2, secondly, to make the hair follicle mouth clear and avoid blockage, you can use topical retinoic acid preparations, such as retinoic acid cream, adapalene gel, etc. can unclog the pores and make the hair follicle mouth clear, so that sebum is easily discharged; 3, for local infection and inflammation for treatment, such as topical fusidic acid cream, benzoyl peroxide gel, clindamycin hydrochloride gel for anti-bacterial and anti-inflammatory treatment, serious can also oral minocycline, doxycycline, clarithromycin, etc. for treatment, which is more effective for inflammatory acne; 4, if the conditions for the treatment of acne, but also with red and blue light irradiation, strong pulse light and other treatments, so The combined treatment is usually more ideal for acne control.