Crossamycin Propionate Granules and Azithromycin belong to the same class of macrolide antibiotics, relatively speaking, Azithromycin has a broader antibacterial spectrum. Crossamycin propionate granules is the propionate derivative of crossamycin, the antibacterial spectrum is similar to erythromycin, the antibacterial effect on staphylococcus spp. and streptococcus spp. is slightly poorer than that of erythromycin, but it still has antibacterial activity on induced drug-resistant strains, and it has a good antibacterial effect on anaerobes. Azithromycin is an azathioprine antibiotic, effective against a wide range of pathogenic bacteria, most gram-positive aerobic bacteria, gram-negative aerobic bacteria, anaerobic bacteria, and also effective against Chlamydia trachomatis, syphilis dense spirochetes, gonococci, and other conditional pathogens associated with HIV infection.