Running knee pain, there is no special quick solution, for knee pain need to identify the cause of the disease and then targeted treatment, treatment methods include conservative treatment, drug treatment and surgical treatment. 1. Meniscus injury: Running knee pain caused by meniscus injury needs to be categorized according to the degree of meniscus injury. For 1st and 2nd degree meniscus injuries, conservative treatment and medication, oral non-steroidal anti-inflammatory drugs, such as celecoxib, can relieve pain and reduce edema in the joints. If there are 3rd degree meniscus injuries, surgical treatment, such as meniscus suture, is needed. 2. Cruciate ligament injury: Cruciate ligament is divided into anterior cruciate ligament and posterior cruciate ligament, no matter who is injured, it will lead to instability and pain in the knee joint, and it needs to be treated conservatively or surgically for a long period of time. If the damage to the cruciate ligament is relatively mild, it can be treated conservatively and restfully, and if there is a rupture of the cruciate ligament, it will need to be surgically stitched up. 3. Rheumatoid arthritis: knee pain caused by rheumatoid arthritis will aggravate the pain after activities, attention should be paid to rest, oral non-steroidal anti-inflammatory drugs, such as celecoxib, to reduce the local immune inflammation. There may be other causes of knee pain after running, it is recommended to consult a doctor to identify the cause and give targeted treatment or therapy, should avoid blind self-medication.