Gastric cancer is a common malignant tumor that seriously endangers the health of Chinese residents, and its incidence rate ranks 2nd among all kinds of tumors in men and 3rd in women, and its incidence rate and mortality rate both rank first among digestive tract tumors. Although chemotherapy has made great progress in the perioperative treatment of gastric cancer in recent years, surgery is still the only possible way to cure gastric cancer, and chemotherapy and radiotherapy cannot fundamentally cure patients. The age of onset of gastric cancer patients is usually around 55 years old, and there is no lack of senior patients, and a considerable number of them have combined cardiovascular, cerebrovascular, respiratory, or metabolic diseases. However, with the continuous improvement of surgical techniques, the continuous updating of surgical and monitoring equipment, and the long-term accumulation of experience in handling elderly patients, the advanced age of patients and their comorbidities are no longer an obstacle to surgery, and most scholars have reached a consensus that for elderly patients, age is no longer an independent factor affecting postoperative complications and mortality. As long as we can grasp the indications for surgery, make adequate preoperative preparations, improve the patient’s cardiopulmonary function and stabilize the patient’s blood sugar and other comorbidities before surgery, the possibility of patient’s accidents will be greatly reduced, and the incidence of postoperative complications will not be significantly increased. One of the pathological characteristics of elderly patients with gastric cancer is that the tumor is generally more differentiated histologically, the pathological type is mainly highly and moderately differentiated adenocarcinoma, the tumor is less malignant, the growth rate is slower, and the healing process is generally better after surgery, so surgery is still the first choice for the treatment of elderly patients with gastric cancer due to various factors such as the risk of surgery and the long-term effect. In fact, patients have to undergo strict examination and adequate preoperative preparation before surgery, and preoperative consultation and discussion will be held to discuss the possible impact of gastric cancer surgery on comorbidities and other comorbidities on gastric cancer surgery. As a family member, it is understandable to worry about the risk of surgery, but it is really a pity to give up surgery for gastric cancer that is suitable for resection because of the fear of risk.