Rhabdomyolysis is one of the more dangerous diseases and generally cannot be relied upon to heal itself. However, most of them can be cured after timely hospitalization, while a small number of people who are not treated in time may suffer from renal impairment, which may even be life-threatening. The causes of rhabdomyolysis are complex, and there are hundreds of causes. Orthopedic-related causes are commonly found in muscle crush injuries, over-exercise, and pyrexia. Its main manifestations are muscle pain, weakness and tea-colored urine. Its treatment is based on the protection of renal function, and it can also be treated surgically if necessary. It is necessary to supplement fluids with large amounts of intravenous fluids as early as possible to expand blood volume. At the same time, diuretics are used as well as alkalinization of urine to promote urination. Patients with combined fascial gap syndrome need to be treated by surgical incision and decompression as early as possible. Through comprehensive treatment, most of the rhabdomyolysis syndrome can be cured, but a small number of patients may be left with renal function damage, or even death from renal failure. Although a small number of rhabdomyolysis cases are mild and may theoretically recover on their own, once the diagnosis is clear, timely treatment is recommended to avoid delays.