Long-term consumption of half a tablet of metoprolol succinate can not be suddenly stopped, and the dose should be gradually reduced to prevent the condition from rebounding. Long-term consumption of half a tablet of metoprolol succinate, the drug will form a stable concentration in the body, the sudden withdrawal of the drug will lead to the disappearance of the drug’s effect, the patient’s original symptoms may recur, or even a worsening of the condition. Patients who have been taking Metoprolol succinate for a long period of time, in order to discontinue the drug, the dosage can be gradually reduced to reach the minimum maintenance dosage. On the basis of the minimum maintenance dose, if the condition is stable, the drug can be gradually discontinued. During the period of discontinuation, close observation of changes in the condition should be made to prevent rebound of the original condition. Adverse reactions of Metoprolol succinate include nausea, vomiting, diarrhea, constipation, dizziness, cold extremities, bradycardia, etc. It is contraindicated in patients who are allergic to the drug components, patients with decompensated heart failure, patients with cardiogenic shock, patients with bronchial asthma, patients with severe bronchospasm, and patients who are taking β-agonists. To stop taking half a tablet of Metoprolol succinate for a long period of time, the treatment program should be adjusted under the supervision of a physician.