Swollen eyes and face when you wake up in bed may be caused by excessive water intake before bedtime, wheals, nephrotic syndrome and other reasons. 1. Excessive water consumption before bedtime: excessive intake of water or other beverages before bedtime may lead to slow and impaired water metabolism, resulting in swelling of the eyelids and face when you wake up in the morning, which is usually a physiological phenomenon and not a cause for undue concern. 2. Staphylococcus aureus: acute suppurative inflammation of the eyelid glands, mainly caused by Staphylococcus aureus infection, when it is more serious, there may be swelling of the eyelids, facial swelling and so on. 3. Nephrotic syndrome: a clinical syndrome caused by various renal diseases, mainly characterized by large amounts of proteinuria, hypoproteinemia, edema, hyperlipidemia, patients may have increased foam in the urine, facial edema, decreased urine output, abdominal distension and other symptoms, also manifested in the eyes and face puffy in bed. It is recommended that patients seek timely medical examination to clarify the cause of the disease and then carry out targeted treatment, pay attention to rest in life to ensure adequate sleep, and pay attention to monitoring the condition and regular review.