One month after chondrosarcoma surgery, there is oozing, consider fat liquefaction, wound infection, osteomyelitis, take anti-infection treatment, incision and drainage. 1. Fat liquefaction: the exudate in this case is mostly yellowish liquid, considering that it is caused by poor drainage, after local rinsing and disinfection, drain the wound with drainage strip. 2. Wound infection: the exudate is mostly white or turbid liquid, consider wound infection, need to remove the incision suture, drain the wound, when the exudate disappears, pull out the drainage. Strictly follow the doctor’s instructions to apply antibiotic treatment, such as levofloxacin and so on. 3. Osteomyelitis: if accompanied by redness, swelling and obvious pain, it is necessary to take radiographs to exclude the possibility of osteomyelitis, and carry out the surgery of removing and draining the lesion, and apply the antibiotic anti-infection treatment according to the doctor’s prescription, such as penicillin. It is recommended to go to the hospital for standardized treatment after chondrosarcoma surgery for one month with local oozing.