Rubella is caused by rubella virus infection, urticaria belongs to allergic diseases, in addition to the different causes, the rash performance, accompanying symptoms, the course of the disease, treatment and other major differences. 1, the pathogen of rubella is the rubella virus, transmitted through the respiratory tract, is an opportunistic infection, most often in children, the symptoms are often mild, the typical symptoms are fever 1 day after the appearance of a generalized rash, usually not accompanied by itching, there may be lymph node enlargement and other symptoms. The rash usually subsides in about 3 days, and is also known as “three-day measles”. In children with more severe symptoms, it may cause viral encephalitis, arthritis and so on. No special treatment can be given, but rest and plenty of water are the mainstays, and attention should be paid to a light diet and isolation from others, especially children. Rubella virus infection in early pregnancy may induce fetal malformation, should pay attention to screening. 2.Hives. Urticaria is an allergic disease, some hives are induced by infection, but there is no specific pathogen, can occur in anyone, good for allergic people, the typical performance is the skin of the wind mass, can fade on its own, fade without leaving traces. Treatment is based on anti-allergic therapy, such as cetirizine tablets, one tablet per night. Rubella and urticaria are more different, but both are relatively simple diseases and not difficult to identify based on the above.