Aspirin enteric-coated tablets are the cornerstone of primary prevention and secondary prevention for all patients with cardiovascular diseases, and as one of the commonly used drugs, they hold the top of the drug list prescriptions with absolute advantages in cardiology. 1. Gastrointestinal symptoms Aspirin enteric-coated tablets, as an oral drug, are metabolized by the gastrointestinal tract, and the speed of dissolution of the coating outside the enteric-coated tablets determines the location of its metabolism in the body. If the enteric coating is metabolized too fast, the drug has not yet reached the intestine, but is still in the stomach, and its damage to the gastric mucosa is direct. Some relevant reports show that among patients who take aspirin enteric tablets orally, up to 15% of patients have digestive symptoms, and these symptoms are mostly manifested as stomach pain, acid reflux, heartburn or bloating and other discomforts. 2, subcutaneous bleeding or organ bleeding Aspirin enteric soluble tablets are used to prevent blood clots by inhibiting platelet function, which will lead to a higher risk of bleeding. The bleeding is various, especially subcutaneous bleeding is more common, which can be manifested as subcutaneous bruising, subcutaneous bleeding spots, etc., while the gastrointestinal bleeding is a common part of the organ bleeding, followed by gum bleeding, brain bleeding, nasal bleeding, hemoptysis and other parts of the bleeding. 3, allergic reaction Allergic reaction itself is a kind of metamorphosis, refers to the body has been immune to the stimulation of the same substance again when the reaction occurs. Allergic people are allergic to pollen, dust and other common things that we have long been used to. Therefore, it is not surprising that people are allergic to aspirin itself, or to the ingredients involved in the production of the drug. 4. Aspirin asthma Aspirin asthma is listed separately because it is different from allergies. The so-called aspirin asthma is called aspirin asthma when an asthma attack is triggered within minutes or hours after taking aspirin orally, regardless of whether there is a previous history of asthma. The main mechanism is that these drugs inhibit cyclooxygenase and block PG synthesis, but do not affect lipoxygenase, resulting in an increase in leukotrienes that cause bronchoconstriction and induce asthma. 5, hemolysis and hemolytic anemia Hemolysis and hemolytic anemia are relatively rare, mostly seen in patients with severe glucose-6-phosphate dehydrogenase (G6PD) deficiency, which is less commonly encountered clinically. In contrast, anemia due to insidious gastrointestinal bleeding is more common. 6, hepatic and renal impairment and other Aspirin enteric soluble tablets rarely report hepatic and renal impairment, while hepatic and renal impairment after bleeding or anemia caused by aspirin enteric soluble tablets may be relatively common, while other adverse reactions caused by it, such as dizziness, vertigo, tinnitus, sweating, nausea and vomiting, headache, etc. after drug overdose are much less common, and most of them can be controlled after reducing the dose or stopping the drug. So pro, aspirin is a great deal more, but you need to be careful with it.