There is no specific time for how long Apatinib Mesylate Tablet should be taken to be effective. Patients’ own conditions are different, and the period to achieve the therapeutic effect after taking it is also different, so the drug can be used correctly and reasonably under the guidance of doctors. Apatinib mesylate tablets are used for patients with advanced gastric adenocarcinoma or adenocarcinoma of the gastroesophageal junction that has progressed or recurred after receiving at least 2 previous systemic chemotherapies. It may also be used in patients with advanced hepatocellular carcinoma who have failed or are intolerant to at least one prior line of systemic therapy. Taking Apatinib Mesylate Tablets may have adverse reactions such as hypertension, thrombosis, circulatory disorders, leukopenia, anemia, proteinuria, elevated blood urea, abdominal pain and diarrhea, nausea and vomiting, stomatitis, abdominal discomfort, gastrointestinal bleeding, constipation, loss of appetite, rash, malaise, edema, dizziness and headache, bradycardia, pharyngitis, back pain, urinary tract infections, insomnia, and others. Abatinib mesylate tablets are contraindicated for those who are allergic to the ingredients, contraindicated for patients with active bleeding, ulcers, intestinal perforation, intestinal obstruction, within 30 days after major surgery, hypertension uncontrollable by medication, grade III-IV cardiac insufficiency, severe hepatic and renal insufficiency, contraindicated for pregnant women, pregnant and lactating patients. If you need to use Apatinib Mesylate Tablets, please consult a professional doctor, follow the doctor’s instructions, and use the medicine reasonably.