SCr refers to the meaning of blood creatinine in medicine, blood creatinine is a kind of metabolic waste of human body, mainly from muscle tissue, blood creatinine production and excretion is relatively constant every day. As most of the blood creatinine needs to be excreted through the kidneys, the value of blood creatinine can reflect the good or bad renal function, when the blood creatinine exceeds the normal range, it suggests that there is renal insufficiency, more than 442 μmoI/L can be diagnosed as renal failure, more than 707 μmoI/L can be diagnosed as uremia. There are many clinical diseases that can cause increased blood creatinine, such as chronic nephritis, diabetic nephropathy, hypertensive renal damage, etc., which need to be based on the patient’s specific condition and etiology to formulate a treatment plan. Once the kidney disease enters into uremia stage, renal replacement therapy needs to be started.