The clinical manifestations of Drei-Ay syndrome, also known as gastrinoma, are abdominal pain and diarrhea. 1. Abdominal pain: due to the large secretion of gastric acid, resulting in the formation of ulcers. Commonly found in the duodenal bulb, most patients present with abdominal pain, and some patients may have ulcer complications such as bleeding and perforation. 2. Diarrhea: large secretion of gastrin leads to gastrointestinal dysfunction and diarrhea. If there is ulcer disease with diarrhea, large amount of gastric acid secretion, recurrence of ulcer disease after surgery, etc., should be considered Zhuo – Ai syndrome. If Zuo – Ai syndrome occurs, should go to the hospital in time, under the guidance of the doctor for treatment, after standardized treatment, the symptoms can mostly be relieved.