Causes of denture stomatitis include systemic factors or local denture overuse, lack of hygiene, and the oral mucosa can produce many white spots or congestion and erosion. This condition often has Candida growth and can be treated with an alkaline sodium bicarbonate mouth rinse or topical application of anti-mold such as mycobacterium. In addition, the patient is advised to replace the full denture in a timely manner, and it must be cleaned after every meal, requires a toothpaste brush, and should be placed in clean, cold water at night when the denture is not in use.