Thyroid nodule calcification 4a cancer exists the possibility of cure, it is recommended to clarify the cause of the disease under the guidance of a doctor, and then carry out thyroidectomy treatment, radiation therapy, thyroid-stimulating hormone suppression therapy. There are 6 grades of thyroid nodules, among which grade 4 can be categorized into 4a, 4b and 4c. 4a is less likely to be cancerous than the others, with a malignancy rate of 2%-10%; the nature of the nodules can be clarified through pathological examination. Calcification of thyroid nodule can be left untreated if it has no effect, and can be surgically removed if it has an occupying effect, etc. If it is clearly cancerous, the cancer should be diagnosed, the cancer type should be clarified, and can be partially excised if the range is small. Some thyroid cancers can also be treated with radiation therapy, and thyroid hormone suppression therapy is required after removal of the thyroid gland. Thyroid nodules are recommended to be standardized under the guidance of a doctor.