A big pimple on the nose should be washed with warm water, adjust the diet, avoid staying up late, medication and so on. 1. Wash your face with warm water: wash your face with warm water when you have a big pimple on your nose. It is recommended to use warm water to wash your face in the morning and evening when cleaning your facial skin, which can wash away excess oil on your face and avoid clogging your pores, leading to aggravation of acne. 2. Adjust the diet: a big pimple on the nose to adjust the diet. It is recommended to eat a light diet, eat more fresh vegetables and fruits, avoid eating spicy, greasy, stimulating food. 3. Avoid staying up late: avoid staying up late when you have a big pimple on your nose. It is recommended to have a regular daily routine, go to bed early and get up early, avoid staying up late. 4. Use of medication: A large pimple on the nose can be treated with medication. You can apply retinoic acid ointment and adapalene gel under the guidance of the doctor, which can play the role of anti-inflammatory and antibacterial, inhibit the sebaceous glands from secreting too much oil, which will help the acne subside. In daily life, avoid spicy food, avoid alcohol, eat less fried and sweet food, drink more water, less stay up late.