People with cystic fibrosis can have varying degrees of gastrointestinal disorders such as dyspepsia, peptic ulcer, gastroesophageal reflux disease, intussusception, and intestinal obstruction. Cystic fibrosis is a hereditary disease that can lead to digestive disorders. Cystic fibrosis can lead to insufficient exocrine glands of the pancreas, with dilatation of the pancreatic ducts and insufficient secretion of pancreatic enzymes, leading to maldigestion and malabsorption. In the long run, it can induce dyspepsia, peptic ulcer, gastroesophageal reflux disease, enteritis, peri-appendiceal abscess, intussusception, intestinal obstruction, etc., with digestive symptoms such as bloating, abdominal pain, nausea, vomiting, diarrhea, constipation, and so on. For the diagnosis of cystic fibrosis, it is recommended to visit a doctor for a comprehensive consideration in combination with genetic testing, sweat electrolyte analysis, and symptoms.