”Do you know what kind of kidney disease will eventually develop into the end? That is chronic renal failure. In this issue, let’s learn what is chronic renal failure, what factors will accelerate the progression of chronic renal failure, and the manifestations of chronic renal failure!” Chronic renal failure is a syndrome consisting of progressive progression of various chronic kidney diseases causing a decrease in glomerular filtration rate and irreversible loss of kidney structure and function, resulting in metabolic disorders and clinical symptoms associated with it. What are the factors that accelerate chronic renal failure, do you know? The human body is an organic whole, the organs and meridians are closely linked to each other, and the upper and lower parts of the body are in communication with each other. Chinese medicine has a long-term disease and the kidney, kidney disease is not only related to the kidney, the internal organs of the lesions can affect the kidney. According to the chronic progression of long-term kidney disease, combined with serum creatinine, urea nitrogen levels and kidney size, it is generally not too difficult to make a diagnosis of chronic kidney failure. What is really meaningful is to accurately determine whether there are reversible factors and whether active causative treatment should be given, as well as whether there are precipitating and aggravating factors based on the chronic course of the disease, such as primary glomerulonephritis, chronic pyelonephritis, hypertensive renal arteriosclerosis, diabetic nephropathy, secondary glomerulonephritis, tubulointerstitial lesions, hereditary renal diseases, and long-term use of antipyretic Chronic damage to the kidney can be caused by the use of analgesics and exposure to heavy metals. The reversible factors that lead to progressive deterioration of renal function in chronic renal failure are infection, drug-related renal damage, metabolic acidosis, dehydration, heart failure, rapid and low blood pressure, etc. The precipitating and aggravating factors based on the chronic course are hypertension, hyperlipidemia, hypercoagulable state, high protein dietary intake, high proteinuria, etc. So, what are the manifestations of chronic renal failure? Patients often appear fatigue, lack of concentration, insomnia, loss of appetite, anorexia, nausea, vomiting, abdominal distension, tongue and mouth ulcers, ammonia odor in the mouth, more serious will appear upper gastrointestinal bleeding, anemia, bleeding tendency, heart failure, spontaneous fracture, skin itching, easy to co-infection, lung infection is more common, such as easier than normal people to catch a cold.