Given that the cause of Parkinson’s disease is not known, there is nothing that can be done to prevent the disease at its root. In view of the fact that Parkinson’s disease may be a multifactorial disease, active and comprehensive preventive measures may be able to achieve good results. The following primary, secondary and tertiary prevention can be carried out: Primary prevention Strengthen environmental protection and labor protection. Some factories that can produce toxic substances should be strictly treated, and the waste slag, waste materials and waste water should be treated non-toxically; improve the working environment and conditions. Pay attention to dietary hygiene, and drinking well water is more reasonable than river water. Prevent and treat certain diseases that may cause Parkinson’s syndrome, such as hypoparathyroidism, arteriosclerosis and brain tumors. Actively prevent exposure to and poisoning by carbon monoxide, carbon disulfide, manganese and cyanide; try to avoid the use of dulcolax-type drugs; crack down on drug trafficking and drug abuse. Actively carry out healthful physical activities and recreational activities among the elderly to improve health status. Secondary prevention The key is early diagnosis and early treatment. The disease has a long compensatory period. Only when the dopaminergic neurons are destroyed to a certain extent and the dopamine content is reduced by 80% will the typical symptoms of Parkinson’s disease appear. Health checkups for middle-aged and elderly people should be conducted, especially to monitor high-risk groups, such as those with a positive family history, those with arteriosclerosis and those who work in toxic environments, and to follow up those who have doubts about muscle tone, coordinated movements and stability, with a view to early detection of the disease. For patients with early diagnosis, neuroprotective agents, Chinese herbal medicine, medical sports, and qigong are used to control the development of the disease; for patients in the early light stage of decompensation, early application of small amounts of levodopa preparations is recommended to relieve symptoms and maintain the ability to live and work. In the course of long-term drug treatment, if the efficacy of treatment is diminished, dopamine receptor enhancers can be added. When the disease is combined with other diseases, care should be taken to avoid drugs that aggravate the symptoms of Parkinson’s disease, such as reserpine, phenothiazines and butylphenols. Phenothiazines and butylphenols block post-synaptic receptors for dopamine and norepinephrine; reserpine reduces brain stores of dopamine, norepinephrine and 5-hydroxytryptamine, all of which can aggravate Parkinson’s disease symptoms. For early stage patients, exercise therapy, physical therapy and psychotherapy should not be neglected, including participation in certain physical work, strengthening exercise of motor and balance functions in daily life, exercise of joint range of motion and muscle strength, and exercise of speech functions. Tertiary prevention The main goal of prevention for patients with intermediate and advanced disease is to delay the process of disability and life-threatening complications. Patients are encouraged to do more active exercises, such as eating, dressing, washing, and brushing their teeth. Although exercise cannot prevent tremors, it can prevent and delay joint stiffness and limb contractures. Also pay attention to the side effects of medication, such as postural hypotension. Overcome emotional excitement and tension, and maintain a happy mood. For late-stage bedridden patients, strengthen turning and passive limb movement to prevent joint immobilization, decubitus ulcers, and decompensated pneumonia.