Contraindications of chronic granulocytic leukemia are mainly manifested from digestive tract function, contraindications of medication, and control of bleeding. 1. Digestive tract function: 90% of people with chronic granulomas have splenomegaly, which will compress the surrounding organs and cause abdominal distension and indigestion. Easy to digest food should be eaten, eat less and more meals. 2. Contraindications: The preferred first-line therapeutic drug for newly diagnosed chronic granulocytic leukemia in chronic phase is imatinib mesylate, which should be discontinued if used by breastfeeding women. This drug may cause dizziness and blurred vision and driving should be avoided. Grapefruit will increase the toxic side effects of this drug and should not be consumed during the medication. 3. Control bleeding: Patients in the accelerated or acute phase, where anemia may be aggravated or accompanied by bleeding, should avoid eating hard foods, which can lead to bleeding in the gastrointestinal tract. They should also avoid overeating, avoiding cold and raw food. Specific diagnosis and treatment need to be carried out under the guidance of a doctor.