Urine protein 2+ may be caused by normal physiological factors such as strenuous exercise, eating a lot of high-protein food; it may also be caused by nephritis or urinary tract infection, etc., at this time it is a pathological phenomenon, not normal. 1. Physiological factors, such as emotional excitement, cold, strenuous exercise, eating a lot of high-protein foods, etc., may lead to urinary protein 2 +, generally can be recovered on their own without treatment, pay attention to rest, eat a light diet, and regular checkups can be. 2. Pathological factors (1) Nephritis, such as acute and chronic glomerulonephritis, lupus nephritis, etc., the glomerular filtration rate is reduced, the basement membrane is destroyed, resulting in excessive protein loss, urine protein will appear 2 + phenomenon, it is recommended to consult a doctor as soon as possible to find out the cause. (2) Urinary tract infection, mostly with urinary frequency, urgency, urinary pain as the main symptoms, urine protein may appear 2 +, need to be treated as soon as possible for anti-infection, commonly used drugs such as levofloxacin, cefuroxime. The above medication need to follow the doctor’s instructions, not unauthorized use of drugs, to avoid aggravating the condition. There are many other reasons for urinary protein 2+, it is recommended to consult a regular hospital in a timely manner and standardize the treatment under the guidance of a physician.