Usually the body is cold and feverish for several reasons: 1, is the initial stage of the cold when the body is infected by bacteria, viruses, fungi, and atypical pathogens, will produce immune complexes, antigen antibody complexes will be the body invasion of toxins out of the body, when the application of antibacterial drugs and anti-infective drugs, the body temperature will be a transient lowering, but the immune complexes when the chemical reaction will rise again, so there will be a cold and fever. The symptoms may occur when the immune complex reacts chemically and the body temperature rises again. 2. endocrine factors, such as premature ovarian failure during menopause and puberty, may also occur when the body is cold and feverish. 3. the clinical symptoms of cold and fever may occur when the hypothalamus, the temperature center, is incompetent or dysfunctional when the brain is traumatized or suffers a massive brain hemorrhage.