Secondary changes of gallbladder wall in cirrhosis refers to the complications caused by the seriousness of cirrhosis, usually related to hepatogenic cholecystitis, gallbladder stones, and secondary gallbladder cancer and other diseases. 1. Hepatogenous cholecystitis: Cirrhosis is more serious, usually associated with viral infection, when the virus invades into the gallbladder area, it is easy to cause cholecystitis, and secondary changes of the gallbladder wall can be found in the examination. It may also be caused by the damage to the gallbladder during the medication of cirrhosis patients. 2. Gallbladder stones: when the condition of cirrhosis gradually aggravates, it will easily lead to the narrowing of intrahepatic bile ducts, which will cause bile stagnation and can not be discharged in time, and then gallstones of hepatic origin will be formed, which will lead to secondary changes of gallbladder wall. 3. Secondary gallbladder cancer: if the condition of cirrhosis is serious and not handled properly, there may be the risk of cancer, and the cancer cells metastasize to the gallbladder, which will lead to secondary changes of gallbladder wall. Secondary changes of gallbladder wall in cirrhosis may be caused by the above factors, but in order to clarify the cause of the disease, it is recommended to do cholecystoscopy, CT of gallbladder and pathological biopsy as soon as possible to understand the situation and then target treatment.