Mouth long blisters may be caused by trauma, may also be the emergence of herpes simplex virus infection, there is no so-called rapid elimination of the method, if the elimination can be for different situations of drug treatment. 1. trauma, if the eating process bites the skin of the mouth, may lead to the skin tissue fluid oozing, so there will be a mouth long blisters symptoms, this situation arises generally need to be treated with antibiotics under the guidance of the doctor, to prevent infections, such as amoxicillin, cephalexin, etc., and at the same time need to maintain a light diet, may be about 2 ~ 3 days will gradually recover. 2. Herpes simplex virus infection, if it is caused by herpes simplex virus infection can be treated with antiviral drugs under the guidance of a doctor, such as acyclovir, vasiclovir, etc., which can control the virus and avoid aggravation of symptoms. Usually need to take good care of the oral cavity, eat less spicy greasy stimulating food.