Patients with renal failure stage III may have fatigue, lumbago, increased nocturia, water-electrolyte disorders and systemic symptoms. 1. The third stage of renal failure due to impaired renal function may present symptoms such as fatigue, lumbago, increased nocturia, and progressive aggravation of edema. 2. Hydroelectrolyte disorders: hyperkalemia, hyponatremia, hypocalcemia, hyperphosphatemia and a series of other manifestations, chronic renal failure stage III patients can die due to hyperkalemia, cerebral edema and pulmonary edema and other complications. 3. Systemic symptoms: loss of appetite, abdominal distension, nausea, vomiting, etc. Due to the abnormalities of renal function in patients with chronic renal failure stage III, erythropoietin synthesis will be reduced, and the patients may suffer from renal anemia, and renal failure will also cause hypertension, heart failure and other diseases. Patients with stage III renal failure should seek timely medical treatment and actively cooperate with doctors to avoid delaying the condition and causing adverse effects.