There is no quick relief for heartburn without a clear diagnosis. First of all, a clear diagnosis is needed, such as gastroesophageal reflux disease, myocardial infarction, pulmonary embolism, etc., which needs to be alleviated by causative treatment, medication, surgery, and other treatments. 1. Gastroesophageal Reflux Disease (GERD): Since acid reflux often causes chest pain and other symptoms, it is necessary to change the related dietary and living habits, including eating less and more frequent meals, taking a walk after meals, etc. In serious cases, it is necessary to apply proton pump inhibitors, such as omeprazole and esomeprazole, etc., under the guidance of a doctor. 2. Myocardial infarction: patients with myocardial infarction will suddenly feel severe pain in the precordial area and a sense of imminent death, etc. They need to take vasodilator drugs, antiplatelet drugs and lipid-lowering drugs, such as nitroglycerin, aspirin, clopidogrel, atorvastatin, etc. In patients with definite myocardial infarction, they need to apply proton pump inhibitors under the guidance of doctors. For patients with clear infarction, timely intervention is needed. 3. Pulmonary embolism: when the patient is bedridden for a long time, hypercoagulable state of the blood, etc., and suddenly develops pain in the heart, it is necessary to consider pulmonary embolism, and it is necessary to immediately anticoagulate after a clear diagnosis, for example, low molecular heparin and rivaroxaban. It is recommended that when the organism has heart pain, timely consultation, identify the cause, and standardize the treatment under the guidance of the doctor.