The most common clinical cause of sudden vague pain below the rib cage is inflammation of the rib cartilage or intercostal neuralgia. The pain is mainly due to a sterile local inflammatory reaction caused by wind, cold and dampness after strenuous exercise or exertion. The main manifestation is a tingling or radiating pain along the lower border of the rib cage. The pain can be triggered by pressure with the hand, and sometimes the pain can radiate along the rib cage to the back and other areas. In this case, rest should be taken and strenuous exercise should be avoided. The pain can be treated locally by applying hot compresses, such as hot water bags or hot towels, or by applying topical Fotarine ointment. If the pain is severe, you can take oral non-steroidal anti-inflammatory and analgesic drugs to treat the symptoms. If the pain is vague on the right side of the lower rib cage, it is necessary to rule out the combination of acute cholecystitis or liver disease. If the pain is vague on the left side of the lower rib cage, it is necessary to exclude the presence of digestive system diseases, such as acute attack of chronic gastritis, gastric ulcer, gastric bleeding, etc.