High-risk HPV testing is mainly used for cervical cancer screening, and the three commonly used methods are combined HPV screening, cytology screening, and HPV screening alone. Combined screening starts at age 30 and ends at age 65. Combined screening can use both typed and untyped HPV tests, with typed tests generally being used. If all co-tests are negative, co-screening should be performed every five years; HPV-positive and cytology is atypical squamous cells, colposcopy can be performed directly; HPV-positive and cytology is negative, co-screening is repeated at 12 months or HPV type 16 and 18 typing is performed. HPV type 16 or 18 is positive, colposcopy should be performed; both type 16 and 18 are negative, co-screening is performed at 12 months. months combined screening. HPV negative cytology for atypical squamous cells, combined screening every 3 years. Women with cytology of low grade squamous intraepithelial lesions of the cervix, high grade squamous intraepithelial lesions of the cervix, and squamous epithelial cell carcinoma should undergo direct colposcopy regardless of HPV results.