In the history of modern medicine, cranial prosthetics has gone through a long developmental journey and the outcome of the repair is influenced by many factors, among which material is very important. A material that performs well in all aspects not only increases the success rate of the procedure, but also greatly reduces the chances of postoperative complications. The materials for cranial repair have gone through iterations, and the rise of each new material and the withdrawal of old materials is a great innovation in technology and a great progress in neurosurgery. At present, titanium mesh is commonly adopted as the cranial implant material in China to perform titanium mesh cranial repair. Titanium mesh is a metal property, although it is highly corrosion resistant and can resist body secretions. However, it still has many defects, firstly, it is a covering repair, which is easy to cut and wear the scalp after surgery, and the titanium mesh is exposed; secondly, it has poor histocompatibility, and infection and rejection occur after surgery; also, the hardness of titanium mesh is high, and it is easy to collapse and deform by external force. In the clinic, many patients have a bulging scalp after titanium mesh repair. So, what should be done about scalp bulging on titanium mesh for skull repair? This situation is mainly due to the depression and deformation of titanium mesh. It is recommended to go to a professional cranial repair hospital for detailed examination and scientific evaluation, and if replacement materials are needed, advanced peek materials can be considered. Peek cranial repair surgery is very mature, it uses new peek as the cranial bone repair implant material, which greatly reduces the postoperative rejection rate and infection rate; at the same time, it adopts embedded repair method, which effectively avoids skin wear and ulceration, depression and deformation, and material exposure caused by traditional titanium mesh covered repair; after years of clinical exploration and summary, our neurosurgery department has upgraded and improved the original peek cranial repair technology, and innovatively introduced peek cranial repair technology. Our neurosurgery department has upgraded and improved the original peek cranial repair technology after years of clinical exploration and summarization, and innovatively introduced the concept of plastic surgery to form a mature technology – peek material cranial repair. We have a set of systematic and complete solutions for various problems such as cosmetic treatment of scalp scar, postoperative head asymmetry and temporal muscle atrophy. In addition, the team has also successfully performed titanium mesh removal and PEEK placement cranial bone repair surgery, achieving remarkable results.