Generally, thalassemia patients should not take iron supplements. Because thalassemia is a hereditary disease, due to the genetic defect that causes the synthesis of peptide chain of pearl protein, the patient has microcytic hypochromic anemia, which is not caused by iron deficiency, and the concentration of iron in the body of thalassemia patients is not low, and the concentration of ferritin is not low, so if iron supplementation is given, it will easily cause too much iron concentration in the patient’s body, which will cause damage to the liver, heart and other important organs. Therefore, thalassemia patients should not be treated with iron supplementation. Iron supplementation can only be applied to patients with iron deficiency anemia, which is a kind of small cell hypochromic anemia caused by insufficient iron intake, iron absorption disorder or loss of red blood cells, resulting in the inability of iron reabsorption and utilization, and a better therapeutic effect can be achieved after giving iron supplementation treatment, but patients with thalassemia cannot be treated with iron supplementation.