Herpes zoster has a certain degree of self-limitation, some patients can be cured on their own, the principle of its treatment is mainly for antiviral, pain relief and anti-inflammatory, according to the patient’s condition, using systemic medication, topical medication, physical therapy and so on, there is no such thing as the best treatment method. 1. Systemic drug treatment: (1) Antiviral drugs: in the early stage of the disease, a sufficient amount of antiviral drugs can be used for treatment, especially for patients older than 50 years old, which can effectively reduce the symptoms of neuralgia and shorten the course of the disease, and commonly used drugs include acyclovir and valacyclovir. (2) Sedative and analgesic drugs: during the acute attack, the patient’s pain is intolerable, the appropriate use of non-steroidal anti-inflammatory drugs for relief, such as diclofenac sodium, etc.; postherpetic neuralgia, you can also choose to use gabapentin or pregabalin for relief. (3) Glucocorticoid drugs: in the early stage, glucocorticoid drugs can be used appropriately to inhibit the inflammatory process, commonly used drugs are prednisone, dexamethasone and so on. 2. Topical medication: mainly anti-viral, drying and anti-inflammatory drugs, before the blisters do not ooze out, you can use glycerine lotion, acyclovir cream and other topical; after the blisters ooze out, you can use 3% boric acid solution or furacillin solution wet compress treatment. 3. Physical therapy: you can choose ultraviolet light, spectrum therapy device, etc., for local irradiation, to promote the blisters to dry up and crust, so as to alleviate the pain and other discomforts. Once herpes zoster, we should pay attention to timely visit the hospital, under the guidance of the doctor for standardized treatment, do not self-medication.