Panic when lying down and sitting up is mainly related to the presence of plasma cavity effusion such as pleural effusion and pericardial effusion in heart failure. Because the heart panic at this time is mainly related to the change of body position, when lying down, the amount of returning blood volume increases, the load on the heart increases, so it is easy to cause panic, wheezing, nocturnal paroxysmal dyspnea, telescopic breathing and other discomfort. But after sitting up, the circulatory load of the heart is reduced, so it is conducive to smoother breathing and can reduce the symptoms of panic and shortness of breath. At this time, it is necessary to seek medical attention in a timely manner to improve the electrocardiogram, cardiac ultrasound, cardiac enzymes, N-terminal brain natriuretic peptide, heart attack triad, chest CT and other examinations to clarify the specific causes and receive timely treatment.