Keratosis pilaris is mostly caused by chronic skin diseases such as keratotic eczema or scaly keratosis pilaris, which can have localized mossy changes with a leather-like appearance. Because of the thickened, rough and even cracked skin, it is difficult to penetrate and absorb when using topical medications, and topical creams with exfoliating effects should be chosen for topical encapsulation treatment. Every night before bedtime, topical application, and then to cling film local sealing 1-2h, can achieve a more satisfactory absorption effect, recommended for 5-7 days of continuous use. It is recommended to develop good hygiene habits, not to wash the skin with hot water or alkaline soap, avoid scratching the skin repeatedly, and apply topical moisturizer after each bath.