Crohn’s disease is an inflammatory disease of the intestinal tract, and patients usually experience significant abdominal pain, abdominal masses, and diarrhea, which can also trigger the appearance of symptoms after eating. In case of relapse after treatment, symptomatic treatment should be continued, including the application of immunomodulatory drugs and aminosalicylic acid preparations. In addition, attention should be paid to monitoring changes in internal environmental indicators, as Crohn’s disease can easily lead to the formation of intestinal fistulas and even induce intestinal obstruction and stricture. Patients will also have significant nausea, vomiting, and fever, and will also require prompt surgical options to relieve the obstruction and remove the fistula. Extra-intestinal manifestations, including multiple perianal fistula formation, may also be present and require regular medication changes after surgery. Patients with Crohn’s disease need to stay away from irritating foods and away from alcohol and tobacco environments.