Thumb pain may be caused by gout, but also by tenosynovitis, rheumatoid arthritis or trauma. 1. Gout: gout can manifest itself as recurrent acute arthritis, gout stones and other causes of thumb pain. (1) Acute arthritis: it is due to the inflammatory reaction caused by the deposition of urate crystals in the joints, often after rest, such as midnight or early morning episodes of severe pain, often self-limiting, more than 2 weeks after the self-relief, which may be accompanied by fever, colchicine can quickly relieve the symptoms. (2) Gouty stone: it is the characteristic manifestation of gout, and less frequently accumulates in the thumb, when it occurs, the affected joints are irregularly swollen and painful, and even cause bone destruction. 2. Tenosynovitis: common in long-term use of the computer mouse crowd, but also for local stab wounds after the stimulation of secondary bacterial infections, often manifested in the sick finger pain, swelling, passive extension of the finger when the pain is aggravated. 3. Rheumatoid arthritis: an autoimmune disease, often early manifestations of symmetrical, multiple double wrists, feet and other joints swelling and pain, often accompanied by morning stiffness. 4. Trauma: It may be caused by trauma to the thumb and its surrounding muscles or tendons and other strains caused by thumb pain. It is recommended that patients with thumb pain go to regular hospitals for consultation, make a clear diagnosis, and follow the doctor’s instructions for standardized treatment.