The proper way to administer oxygen to a patient with cerebral infarction is to give continuous low-flow nasal cannula oxygen or mask oxygen, which is generally indicated in patients with large hemispheric infarcts and brainstem infarcts with decreased oxygen saturation on blood gas checks. If the patient has a large cerebral infarction, the patient’s clinical signs and symptoms are generally severe and most patients can present with impaired consciousness, including drowsiness, lethargy, and coma. Most of the patients have cerebral edema and increased intracranial pressure, and in the case of severe increased intracranial pressure, it can cause increased symptoms of ischemia and hypoxia in the patient’s brain, which can cause ischemic and hypoxic changes in the patient and decreased oxygen saturation in the patient’s blood. In the case of brainstem infarction, unstable vital signs and irregular respiration generally occur, and severe respiratory irregularities also tend to cause hypoxia in patients, and hypoxemia should generally be treated with oxygenation. If patients with brain infarction do not have hypoxemia, it is not routinely advocated to give oxygen therapy.