Vague pain in the location of the gallbladder is associated with disease of the gallbladder itself, stones, and liver disease. Under normal circumstances, the location of the gallbladder does not show hidden pain performance, and if local pain occurs, it should be closely observed. Because it is easy to have epigastric pain and discomfort, local distension and vague pain after eating fatty food, it should be considered as gallbladder itself disease, gallbladder disease is mainly common gallbladder inflammation, significant thickening of gallbladder wall, local bumpiness, chronic inflammation long-term stimulation, it will cause local pain. It is considered to be caused by stones, commonly bile duct stones and gallbladder stones. When stones are blocked, the bile cannot be discharged normally, which will cause swelling and hidden pain in the right upper abdomen, and some patients will experience nausea and vomiting, which can be clearly diagnosed by going to the hospital for ultrasound and MRI examination. Diseases of the liver and gallbladder can also cause localized vague pain, such as simple masses, and as the masses gradually increase in size, they can cause pressure on nerves and localized pain.