Pain in the shoulder may be caused by the following reasons: 1. The pain is caused by prolonged compression of the shoulder joint during sleep at night, resulting in poor blood circulation. 2. The pain may be caused by a drop pillow or localized stimulation by wind and cold. 3. The pain may also be caused by cervical spondylosis or frozen shoulder, or by improper exertion of the shoulder muscles due to high-intensity sports during the day. After this happens, the patient can take appropriate oral anti-inflammatory and analgesic drugs to relieve, such as loxoprofen sodium, or local application of fotarine ointment to relieve pain can be.